2018;119(3):271-279. Wu, W. H., Lu, S. C., Wang, T. F., Jou, H. J., and Wang, T. A. The role of essential fatty acids in development. Innis, S. M., Nelson, C. M., Rioux, M. F., and King, D. J. Giovannini, M., Verduci, E., Salvatici, E., Fiori, L., and Riva, E. Phenylketonuria: dietary and therapeutic challenges. Judge, M. P., Harel, O., and Lammi-Keefe, C. J. Early research shows that taking a combination supplement containing DHA and many other ingredients along with a conventional medication might reduce thickness of the macula of the eye. Some research shows that taking DHA helps to increase the amount of DHA in the blood of children with PKU. O'Shea, K. M., Khairallah, R. J., Sparagna, G. C., Xu, W., Hecker, P. A., Robillard-Frayne, I., Des, Rosiers C., Kristian, T., Murphy, R. C., Fiskum, G., and Stanley, W. C. Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition. Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline. Pediatrics. Woodman RJ, Mori TA, Burke V, et al. Agren JJ, Hanninen O, Julkunen A, et al. Learn how to manage your emotions, set and achieve your goals, and ultimately earn the respect of those around you. View abstract. Birch, D. G. A randomized placebo-controlled clinical trial of docosahexaenoic acid (DHA) supplementation for X-linked retinitis pigmentosa. Mozaffari-Khosravi H, Yassini-Ardakani M, Karamati M, Shariati-Bafghi SE. B., Barden, A., Watts, G. F., and Beilin, L. J. View abstract. J Lipid Res 2003;44(3):455-463. Young, G. and Conquer, J. Omega-3 fatty acids and neuropsychiatric disorders. View abstract. Am J Clin Nutr 2000;71:1085-94. The inclusion of plentiful DHA in the diet improves learning ability, whereas deficiencies of DHA are associated with deficits in … View abstract. Horrocks, L. A. and Farooqui, A. A., Martin, J. View abstract. Early research shows that taking DHA daily for 4 months might reduce symptoms and improve brain imaging related to spinocerebellar ataxia. Br J Nutr. View abstract. View abstract. Sanjurjo P, Ruiz-Sanz JI, Jimeno P, et al. Arch Dis Child 2003;88(7):582-583. View abstract. View abstract. J Nutr 2011;141(2):207-213. Please consult with your doctor for recommendations specific to your body. Larque, E., Demmelmair, H., Berger, B., Hasbargen, U., and Koletzko, B. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiovascular disease risk in the canola oil multicenter randomized controlled trial. J Pediatr 2001;139:189-96. Biggemann, B., Laryea, M. D., Schuster, A., Griese, M., Reinhardt, D., and Bremer, H. J. View abstract. Geppert, J., Kraft, V., Demmelmair, H., and Koletzko, B. Docosahexaenoic acid supplementation in vegetarians effectively increases omega-3 index: a randomized trial. 2013 Oct;44(10):2710-7. Unfortunately, it is not as commonly found as other types of omega-3 fatty acids. View abstract. Grimsgaard, S., Bonaa, K. H., Hansen, J. Hoffman DR, Hughbanks-Wheaton DK, Spencer R, et al. Growth and development of preterm infants fed infant formulas containing docosahexaenoic acid and arachidonic acid. 6217-54-5 Docosahexaenoic Acid (DHA) is essential for the growth and functional development of the brain in infants. Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. Br J Nutr. People who get more DHA from their diet might have a lower risk of developing dementia. B., Grimsgaard, S., Nilsen, H., Nordoy, A., and Bonaa, K. H. Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on fatty acid absorption, incorporation into serum phospholipids and postprandial triglyceridemia. Lipids 1996;31(1):99-105. Judge, M. P., Harel, O., and Lammi-Keefe, C. J. Maternal consumption of a docosahexaenoic acid-containing functional food during pregnancy: benefit for infant performance on problem-solving but not on recognition memory tasks at age 9 mo. J Nutr. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. 49(1), e287 (2017). Pediatrics 2000;105(6):1292-1298. View abstract. Pifferi, F., Jouin, M., Alessandri, J. M., Haedke, U., Roux, F., Perriere, N., Denis, I., Lavialle, M., and Guesnet, P. n-3 Fatty acids modulate brain glucose transport in endothelial cells of the blood-brain barrier. Effects of a diet integration with an oily emulsion of DHA-phospholipids containing melatonin and tryptophan in elderly patients suffering from mild cognitive impairment. Lipids 1998;33(2):131-138. 2013 Jan 14;109(1):155-61. View abstract. View abstract. Gould JF, Makrides M, Colombo J, Smithers LG. Int.J.Vitam.Nutr.Res. View abstract. But it doesn't seem to help with memory or thinking skills. Food Nutr Bull 2010;31(2 Suppl):S108-S116. A critical appraisal of the role of dietary long-chain polyunsaturated fatty acids on neural indices of term infants: a randomized, controlled trial. Carlson SE, Colombo J, Gajewski BJ, Gustafson KM, Mundy D, Yeast J, Georgieff MK, Markley LA, Kerling EH, Shaddy DJ. Docosahexaenoic acid definition is - an omega-3 fatty acid C22H32O2 found especially in fish of cold waters —abbreviation DHA. View abstract. 2001;16(2-3):201-204. 2013 Feb;88(2):163-9. view abstract. (Tokyo) 1999;45(5):655-665. View abstract. View abstract. View abstract. Makrides, M., Gibson, R. A., McPhee, A. J., Yelland, L., Quinlivan, J., and Ryan, P. Effect of DHA supplementation during pregnancy on maternal depression and neurodevelopment of young children: a randomized controlled trial. J Pediatr 2001;139(4):532-538. Hamazaki T, Sawazaki S, Itomura M, et al. 1999;15(3):177-184. Conditions in a man that prevent him from getting a woman pregnant within a year of trying to conceive (male infertility). Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in hyperlipidemic, overweight men. DHA, or docosahexaenoic acid, is really the opposite. Am J Clin Nutr 2008;87(5):1521-1529. Cao Y, Hou L, Wang W. Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies. Early research suggests that taking DHA, eicosapentaenoic acid (EPA), and alpha-lipoic acid for 2 years does not prevent symptoms from returning in people with schizophrenia who stop taking their medication. View abstract. Nelson GJ, Schmidt PS, Bartolini GL, et al. Early research suggests that taking DHA does not improve most symptoms of autism. View abstract. View abstract. Clin Pediatr (Phila) 2008;47(4):355-362. B., Watts, G. F., Best, J. D., and Beilin, L. J. Docosahexaenoic acid but not eicosapentaenoic acid increases LDL particle size in treated hypertensive type 2 diabetic patients. Br J Cancer. Four-year follow-up of children born to women in a randomized trial of prenatal DHA supplementation. Lauritzen L, Hoppe C, Straarup EM, Michaelsen KF. Br J Nutr 2000;83:337-9. Decsi, T., Campoy, C., and Koletzko, B. View abstract. 2014 May 7;311(17):1802-4. Michael-Titus, A. T. Omega-3 fatty acids and neurological injury. J Am Heart Assoc. van Goor, S. A., Dijck-Brouwer, D. A., Doornbos, B., Erwich, J. J., Schaafsma, A., Muskiet, F. A., and Hadders-Algra, M. Supplementation of DHA but not DHA with arachidonic acid during pregnancy and lactation influences general movement quality in 12-week-old term infants. Trademarks & Tradenames used herein are the property of their respective holders. Andreeva VA, Touvier M, Kesse-Guyot E, et al. B., Croft, K. D., and Beilin, L. J. View abstract. View abstract. 2012 Jun;107(11):1682-93. Haggarty, P. Effect of placental function on fatty acid requirements during pregnancy. Kimura, S., Saito, H., Minami, M., Togashi, H., Nakamura, N., Ueno, K., Shimamura, K., Nemoto, M., and Parvez, H. Docosahexaenoic acid attenuated hypertension and vascular dementia in stroke-prone spontaneously hypertensive rats. Br J Nutr 2008;99(2):421-431. Usually, government's categorizes medicines that can be addictive as controlled substances. Bazan, N. G., Rodriguez de Turco, E. B., and Gordon, W. C. Pathways for the uptake and conservation of docosahexaenoic acid in photoreceptors and synapses: biochemical and autoradiographic studies. Memory and thinking skills (cognitive function). Zhang Z, Fulgoni VL, Kris-Etherton PM, Mitmesser SH. View abstract. J.Nutr. Lipids 1989;24(12):998-1003. 2015;25(4):261-74. Docosahexaenoic Acid is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: Coronary artery disease. View abstract. 2012 Jul;88(7):531-7. Alzheimer disease. 2014 Jan;34(1):17-24. van den Ham EC, van Houwelingen AC, Hornstra G. Evaluation of the relation between n-3 and n-6 fatty acid status and parity in nonpregnant women from the Netherlands. 2014;14:168. Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study. Nobili, V., Bedogni, G., Alisi, A., Pietrobattista, A., Rise, P., Galli, C., and Agostoni, C. Docosahexaenoic acid supplementation decreases liver fat content in children with non-alcoholic fatty liver disease: double-blind randomised controlled clinical trial. 1996;126(11):2784-2789. 2018;10(10). A., Brown, N. E., Thomson, A. Jumpsen, J. Am J Obstet Gynecol 2013;208(4):313.e1-9. World Rev Nutr Diet 2009;99:55-70. View abstract. Am.J.Ophthalmol. Lipids 2007;42(2):109-115. Autism. View abstract. View abstract. Birch EE, Carlson SE, Hoffman DR, Fitzgerald-Gustafson KM, Fu VL, Drover JR, Castañeda YS, Minns L, Wheaton DK, Mundy D, Marunycz J, Diersen-Schade DA. Gawrisch, K., Soubias, O., and Mihailescu, M. Insights from biophysical studies on the role of polyunsaturated fatty acids for function of G-protein coupled membrane receptors. Jorgensen, M. H., Hernell, O., Lund, P., Holmer, G., and Michaelsen, K. F. Visual acuity and erythrocyte docosahexaenoic acid status in breast-fed and formula-fed term infants during the first four months of life. A randomized trial of supplementation with docosahexaenoic acid-rich tuna oil and its effects on the human milk cytokines interleukin 1 beta, interleukin 6, and tumor necrosis factor alpha. View abstract. View abstract. Am J Clin Nutr 2009;89(3):913-919. A basic course for everyone to learn Microsoft Excel and LOOKUP function. Am J Clin Nutr 1995;62:761-8. Yaemsiri S, Sen S, Tinker LF, Robinson WR, Evans RW, Rosamond W, Wasserthiel-Smoller S, He K. Serum fatty acids and incidence of ischemic stroke among postmenopausal women. 2003;41(11):1433-1446. Morris MC, Evans DA, Bienias JL, et al. Montgomery P, Spreckelsen TF, Burton A, Burton JR, Richardson AJ. Cleary, M. A., Feillet, F., White, F. J., Vidailhet, M., Macdonald, A., Grimsley, A., Maurin, N., de Baulny, H. O., and Rutherford, P. J. Randomised controlled trial of essential fatty acid supplementation in phenylketonuria. Egert, S., Kannenberg, F., Somoza, V., Erbersdobler, H. F., and Wahrburg, U. Dietary alpha-linolenic acid, EPA, and DHA have differential effects on LDL fatty acid composition but similar effects on serum lipid profiles in normolipidemic humans. Toft I, Bonaa KH, Ingebretsen OC, et al. View abstract. Increased intake of DHA as part of the diet is linked with a lower risk of developing Crohn disease. Birch, E. E., Hoffman, D. R., Uauy, R., Birch, D. G., and Prestidge, C. Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. Lipids 1996;31:85-90. Early research suggests that taking DHA does not improve memory and thinking skills in people with bipolar disorder. View abstract. Docosahexaenoic acid, ethyl ester. Also, levels of DHA in the blood of the pregnant mother do not appear to be associated with risk of type 1 diabetes in the child. View abstract. Lipids 2007;42(11):1011-1024. View abstract. View abstract. 2018;18(3):282-288. Wheaton DH, Hoffman DR, Locke KG, et al. View abstract. Arch Dis Child Fetal Neonatal Ed 2003;88:F383-90. View abstract. Vision problems in people with diabetes (diabetic retinopathy). Docosahexaenoic Acid. View abstract. View abstract. Jans, L. A., Giltay, E. J., and Van der Does, A. J. It is sold as DHA Sigma-Aldrich. Information from this source is evidence-based and objective, and without commercial influence. While arachidonic acid (AA) is released from membrane phospholipids by cytosolic phospholipase A 2 (cPLA 2), DHA is linked to action of the Ca 2+-independent iPLA2. Lipids 2001;36(11):1183-1193. Prostaglandins Leukot.Essent.Fatty Acids 2007;77(5-6):233-238. Invest Ophthalmol Vis Sci. J Pediatr 2010;157(6):900-905. Schwellenbach, L. J., Olson, K. L., McConnell, K. J., Stolcpart, R. S., Nash, J. D., and Merenich, J. Respiratory hospitalisation of infants supplemented with docosahexaenoic acid as preterm neonates. View abstract. 2002;24(5):683-693. View abstract. Drover JR, Felius J, Hoffman DR, Castañeda YS, Garfield S, Wheaton DH, Birch EE. The opinions expressed in the surveys shown on the, The latest and the best classes on TabletWise.com, The Complete Lunchtime Soft Skills Course. Obesity. View abstract. 2007;26(4):229-234. View abstract. View abstract. Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: the Nuheal trial. Int.J.Dev.Neurosci. View abstract. J Nutr 2009;139(3):495-501. Yui K, Koshiba M, Nakamura S, Kobayashi Y. Wurtman, R. J., Cansev, M., Sakamoto, T., and Ulus, I. H. Administration of docosahexaenoic acid, uridine and choline increases levels of synaptic membranes and dendritic spines in rodent brain. View abstract. DHA is also required for maintenance of normal brain function in adults. J Med Food. Kimura S, Tamayama M, Minami M, et al. Lipids 2004;39(2):117-123. View abstract. Arch Neurol. It can also be made by algae. View abstract. Bazan, N. G. Neuroprotectin D1-mediated anti-inflammatory and survival signaling in stroke, retinal degenerations, and Alzheimer's disease. Lipids 1999;34 Suppl:S345-S346. Stough C, Downey L, Silber B, Lloyd J, Kure C, Wesnes K, Camfield D. The effects of 90-day supplementation with the omega-3 essential fatty acid docosahexaenoic acid (DHA) on cognitive function and visual acuity in a healthy aging population. Dev.Med Child Neurol. A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until two months. Lucas A, Stafford M, Morley R, et al. Am.J.Clin.Nutr. View abstract. View abstract. View abstract. Mori, T. A., Bao, D. Q., Burke, V., Puddey, I. Int J Food Sci Nutr. Lipids 1999;34(8):793-799. 2004;137(4):704-718. Prostaglandins Leukot.Essent.Fatty Acids 2007;77(5-6):279-286. 2004;122(9):1297-1305. Simopoulos, A. P. Human requirement for N-3 polyunsaturated fatty acids. Am J Clin Nutr 2009;89(1):64-70. Johnson, E. J., McDonald, K., Caldarella, S. M., Chung, H. Y., Troen, A. M., and Snodderly, D. M. Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women. View abstract. Hypertension 1993;22:371-9. Innis, S. M., Gilley, J., and Werker, J. A randomized, controlled trial of omega-3 fatty acids plus an antioxidant for relapse prevention after antipsychotic discontinuation in first-episode schizophrenia. In fact, DHA might increase the risk for this disease in some infants. 2012;129(3):e827-41. J Clin Invest 2005;115(10):2774-2783. 2014 Jan 10;9(1):e83764. View abstract. J.Mol.Neurosci. View abstract. Pediatrics. View abstract. Int J Cancer. 2009 Dec 15;101(12):1978-85. Effects of lutein and docosahexaenoic Acid supplementation on macular pigment optical density in a randomized controlled trial. Hoffman, D. R., Theuer, R. C., Castaneda, Y. S., Wheaton, D. H., Bosworth, R. G., O'Connor, A. R., Morale, S. E., Wiedemann, L. E., and Birch, E. E. Maturation of visual acuity is accelerated in breast-fed term infants fed baby food containing DHA-enriched egg yolk. Prisco D, Paniccia R, Bandinelli B, et al. This survey is being conducted by the WebMD marketing sciences department. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. J Perinat.Med 2007;35 Suppl 1:S5-11. View abstract. Status of plasma and erythrocyte fatty acids and vitamin A and E in young children with cystic fibrosis. What precautions should you take while using Docosahexaenoic Acid? View abstract. Phosphatidylserine containing w-3 fatty acids may improve memory abilities in non-demented elderly with memory complaints: a double-blind placebo-controlled trial. Nutrition 2006;22(1):36-46. 2005;45(1):1-28. Please consult your physician or pharmacist or refer to product package. Many children with attention-deficit/hyperactivity disorder - a placebo-controlled double-blind study disease ( Crohn disease ) for restenosis discuss. Davis PG, Thio M, Bouwstra H, Nakamura S, Bonaa, K.,,! A., Brown, N. G. Cell survival matters: docosahexaenoic acid on the loss of in. Hung S, Lundbye-Christensen S, Pyorala K, Imai H, al. Cognitive decline metabolites from fish oil ) for Perinatal depression lower blood sugar or in. 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