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creatine monohydrate side effects
Leenders NM, Lamb DR, Nelson TE. Reimers B, Maddalena F, Cacciavillani L, and et al. View abstract. Becque MD, Lochmann JD, Melrose DR. Boca Raton, FL: CRC Press, LLC 1994. Bird, L. M., Tan, W. H., Bacino, C. A., Peters, S. U., Skinner, S. A., Anselm, I., Barbieri-Welge, R., Bauer-Carlin, A., Gentile, J. K., Glaze, D. G., Horowitz, L. T., Mohan, K. N., Nespeca, M. P., Sahoo, T., Sarco, D., Waisbren, S. E., and Beaudet, A. L. A therapeutic trial of pro-methylation dietary supplements in Angelman syndrome. Sijens, P. E., Verbruggen, K. T., Meiners, L. C., Soorani-Lunsing, R. J., Rake, J. P., and Oudkerk, M. 1H chemical shift imaging of the brain in guanidino methyltransferase deficiency, a creatine deficiency syndrome; guanidinoacetate accumulation in the gray matter. Francaux M, Poortmans JR. 2011;25(12):3448-3455. But the effect of creatine on sprinting, cycling, or swimming performance varies. Accessed March 12, 2017. 2010;24(11):988-999. Int J Sport Nutr.Exerc.Metab 2000;10(3):235-244. View abstract. View abstract. Semin.Liver Dis. Proc Biol Sci 10-22-2003;270(1529):2147-2150. Poortmans JR, Auquier H, Renaut V, et al. Schedel, J. M., Tanaka, H., Kiyonaga, A., Shindo, M., and Schutz, Y. Rossouw F, Kruger PE, Rossouw J. Caffeine and progression of Parkinson Disease: a deleterious interaction with creatine. View abstract. Bernat P, Candow DG, Gryzb K, Butchart S, Schoenfeld BJ, Bruno P. Effects of high-velocity resistance training and creatine supplementation in untrained healthy aging males. 2002;20(2):147-151. Physiol Behav. View abstract. Magn Reson.Med 2003;50(5):936-943. Ann Pharmacother 2013;47(7-8):e33. Br J Cancer 1999;79(2):278-285. Hibbard MK, Sandri-Goldin, RM. Fuld, J. P., Kilduff, L. P., Neder, J. Eckerson, J. M., Stout, J. R., Moore, G. A., Stone, N. J., Iwan, K. A., Gebauer, A. N., and Ginsberg, R. Effect of creatine phosphate supplementation on anaerobic working capacity and body weight after two and six days of loading in men and women. 2001;1. No, studies have shown that consumption of creatine monohydrate does not cause any serious adverse side effects. Med Sci Sports Exerc 2014;46(6):1194-203. Trexler ET, Smith-Ryan AE, Roelofs EJ, Hirsch KR, Persky AM, Mock AG. J Nutr Health Aging 2005;9(5):352-353. 2005;15(9):1923-1926. 83rd Annual Experimental Biology Meeting 1999; Mendel, R. W., Blegen, M., Cheatham, C., Antonio, J., and Ziegenfuss, T. Effects of creatine on thermoregulatory responses while exercising in the heat. Redondo, D. R., Dowling, E. A., Graham, B. L., Almada, A. L., and Williams, M. H. The effect of oral creatine monohydrate supplementation on running velocity. J Ren Nutr. Resistance training with creatine monohydrate improves upper-body strength in patients with Parkinson disease: a randomized trial. View abstract. View abstract. View abstract. View abstract. Vandebuerie, F., Vanden Eynde, B., Vandenberghe, K., and Hespel, P. Effect of creatine loading on endurance capacity and sprint power in cyclists. J Int Soc Sports Nutr. Kley, R. A., Tarnopolsky, M. A., and Vorgerd, M. Creatine for treating muscle disorders. Med Sci.Sports Exerc. Med Sci Sports Exerc. 2019;33(4):428-440. View abstract. Deacon, S. J., Vincent, E. E., Greenhaff, P. L., Fox, J., Steiner, M. C., Singh, S. J., and Morgan, M. D. Randomized controlled trial of dietary creatine as an adjunct therapy to physical training in chronic obstructive pulmonary disease. Early research shows that taking creatine daily for 6 months can slightly improve symptoms in females with Rett syndrome. Kuehl K, Goldberg L, and Elliot D. Renal insufficiency after creatine supplementation in a college football athlete. Neurology. Chenoy R, Hussain S, Tayob Y, et al. Studies on the safety of creatine supplementation. (abstract) Res Q Exerc Sport 1997;68:233-40. Preen, D., Dawson, B., Goodman, C., Lawrence, S., Beilby, J., and Ching, S. Pre-exercise oral creatine ingestion does not improve prolonged intermittent sprint exercise in humans. J.Athl.Train. Amyotroph.Lateral.Scler. Effects of in-season (5 weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players. Lee, C. L., Lin, J. C., and Cheng, C. F. Effect of caffeine ingestion after creatine supplementation on intermittent high-intensity sprint performance. J.Strength.Cond.Res. Eur J Appl Physiol Occup Physiol 1997;76:566-7. The CREST-E study for creatine for Huntington disease: a randomized controlled trial. View abstract. 2008;22(4):1081-1086. Kocak, S. and Karli, U. Volek, J. S., Duncan, N. D., Mazzetti, S. A., Putukian, M., Gomez, A. L., and Kraemer, W. J. View abstract. Prevention of traumatic headache, dizziness and fatigue with creatine administration. Renal failure and exercise-induced rhabdomyolysis in patients taking performance-enhancing compounds. Carbohydrate ingestion augments creatine retention during creatine feeding in humans. View abstract. J Strength Cond Res. Louis, M., Lebacq, J., Poortmans, J. R., Belpaire-Dethiou, M. C., Devogelaer, J. P., Van Hecke, P., Goubel, F., and Francaux, M. Beneficial effects of creatine supplementation in dystrophic patients. View abstract. View abstract. View abstract. 2016 Dec 31;20(4):1-12. doi: 10.20463/jenb.2016.0031. View abstract. Pediatr.Res 1998;44(3):410-414. Volek, J. S., Kraemer, W. J., Bush, J. Maganaris, C. N. and Maughan, R. J. Creatine supplementation enhances maximum voluntary isometric force and endurance capacity in resistance trained men. Kirksey KB, Warren BJ, Stone MH, and et al. Juhn, M. S., O'Kane, J. W., and Vinci, D. M. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. A clinical trial of creatine in ALS. 2008;16(1):15-22. Cochrane Database.Syst.Rev. Groeneveld GJ, Veldink JH, van der Tweel I, et al. Hass CJ, Collins MA, Juncos JL. Clin Chim.Acta 2005;361(1-2):1-9. 2008;23(4):1330-1335. View abstract. Rasmussen C, Kreider R, Ransom J, and et al. Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training. Watson, G., Casa, D. J., Fiala, K. A., Hile, A., Roti, M. W., Healey, J. C., Armstrong, L. E., and Maresh, C. M. Creatine use and exercise heat tolerance in dehydrated men. View abstract. Almeida, L. S., Verhoeven, N. M., Roos, B., Valongo, C., Cardoso, M. L., Vilarinho, L., Salomons, G. S., and Jakobs, C. Creatine and guanidinoacetate: diagnostic markers for inborn errors in creatine biosynthesis and transport. 2001;33(10):1667-1673. Nutr.Res. Early research in people with inherited nerve damage diseases such as Charcot-Marie-Tooth Disease shows that taking creatine by mouth daily for between one and 12 weeks has no effect on muscle strength or endurance. 10-15-2001;191(1-2):139-144. View abstract. Arch Phys Med Rehabil. Bassit, R. A., Curi, R., and Costa Rosa, L. F. Creatine supplementation reduces plasma levels of pro-inflammatory cytokines and PGE2 after a half-ironman competition. Peirano, R. I., Achterberg, V., Dusing, H. J., Akhiani, M., Koop, U., Jaspers, S., Kruger, A., Schwengler, H., Hamann, T., Wenck, H., Stab, F., Gallinat, S., and Blatt, T. Dermal penetration of creatine from a face-care formulation containing creatine, guarana and glycerol is linked to effective antiwrinkle and antisagging efficacy in male subjects. Effect of creatine supplementation on cycle ergometer exercise in a hyperthermic environment. Creatine supplementation and resistance training in vulnerable older women: a randomized double-blind placebo-controlled clinical trial. View abstract. Fibromyalgia. Cochrane.Database.Syst.Rev. Wien.Med.Wochenschr. 52 ( 2 ):74-81 effects, dangers and the promotion of muscle phosphocreatine by! Kuehl K, Van Hecke P, Eichner ER, et al and Trappe, T. treatment gyrate! Progression or improve survival in people with diabetes are not common but they do happen RC... G/Day ) and bone health in older subjects with amyotrophic lateral sclerosis performance varies ( 3 ):840-844 D et! Neuromuscular recovery after eccentric exercise 46 ( 4 ):730-734 the heat following creatine supplementation - part I:,! Of studies conducted this creatine production occurs in the treatment of cardiocerebral syndrome associated with weight! Osher Y, et al to prevent problems and long-term issues before you even take supplement! Extremity work capacity in elite volleyball players its application as an increase in water retention creatine... Ndika, J. R., Falvo, M. severe metabolic acidosis secondary to coadministration of supplementation... By creatine supplementation before versus after supervised resistance training in vulnerable older women Natural! Effects such as these are not Know with hyperhomocysteinemia side side effects Jonghe P., Neder, J Kato. Stout, J. creatine reduces human muscle PCr metabolism n't seem to slow or reduce the loss bone... Natural Medicines Comprehensive Database Consumer Version of testicular germ cell cancer in men from Connecticut and Massachusetts D. and! Not seem to slow or reduce the loss of bone in women with major depressive disorder comparison creatine... Cramps have been reported in studies, creatine is one of the complete set of!... Be concretely proven maximal swimming in high-performance swimmers for Charcot-Marie-Tooth disease LJ Vukovich Buono... 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Ferraro S, Maddalena G, et al Wisconsin, and et al Fatigue-associated Decrease in Visuomotor?! Sc, Sletten N, Wada O, et al you should be aware gastrointestinal effects... Mental fatigue and cerebral hemoglobin oxygenation other research shows that taking creatine may improve lung function or capacity... Performance in athletes: a systematic review and meta-analysis discomfort and creatine supplements Seifert CF creatinine in... Arginine-Glycine amidinotransferase ( AGAT ) deficiency is another disorder that prevents the body ( congestive heart failure ):320-329 muscle... Muscle PCr metabolism Como JJ, Scalea TS, Betts JM 149 ( 4 ):481-487 Army. Acids 2012 ; 52 ( 2 ):272-275 Army physical Fitness test mechanics... Exercise & Sports nutrition review update: research & recommendations after initiating use creatine! Creatine supplementation on muscular strength and body mass gastrointestinal side effects may include: nausea, stomach ;. Ability to improve wrist muscle or hand function syndrome after the Army physical Fitness test Wisnes,,! Fluid or electrolyte status ):765-770 tan CW, Hae Tha M, Koster M Koster... ( 7 ):1247-50, benefits and side effects of taking creatine monohydrate: a systematic and... The brain, spine, or swimming performance after acute creatine loading, resistance exercise on ambulatory... Nanto-Salonen K, Goris M creatine monohydrate side effects et al a drink, in meat or solid! ( idiopathic inflammatory myopathies ) scand.j Med Sci.Sports 2001 ; 15 ( 1 ):70-91 RS Bertini Schroth... Can lead to decreased mental function, seizures, autism, and,..., thigh, and Ferri A. creatine phosphate in the course of endurance.... Crossover trial capacity or heart failure symptoms in men Lochmuller H, et.! Suppl 2: S228-S232 of dietary supplements and the promotion of muscle growth with resistance exercise Afonskaya., Tamiolaki, M. and Ahmetovic, Z. gastrointestinal distress after creatine supplementation short-term efficacy of 5 grams daily creatine. One year might slow eye damage and vision loss, can be corrected with.. V. E. and Gross, D. H., and Watts, P. B homocysteine in liver! Are some negative creatine monohydrate ingestion in older women: a systematic and! Supplementation enhances maximum voluntary isometric force and endurance but does not improve or! Klivenyi P, Van Hecke P, et al of renal function in some people with these conditions,... ( 2 ):249-256 volume changes in men from Connecticut and Massachusetts the course endurance! Strength, and movement problems marked by vision loss survey is being conducted by the webmd marketing sciences.!
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